首页> 外国专利> ATTENUATE LIVE VACCINE OF VSOCS GENE-DELETED MEGALOCYTIVIRUS, METHOD TO PREPARE THE SAME AND USE THEREOF

ATTENUATE LIVE VACCINE OF VSOCS GENE-DELETED MEGALOCYTIVIRUS, METHOD TO PREPARE THE SAME AND USE THEREOF

机译：弱毒的 VSOCS 基因缺失的巨细胞病毒活疫苗，制备方法及其使用方法

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The present invention provides an attenuate live vaccine of vsocs gene-deleted Megalocytivirus, methods to prepare the same and uses thereof. The preparing method involves obtaining recombinant virus having vsocs gene replaced by green fluorescent protein (GFP) gene, and separating and purifying vsocs gene-deleted virus to obtain attenuated live vaccine. The vaccine is useful for preventing Megalocytivirus infection in fish. 展开▼

机译：本发明提供了缺失 vsocs 基因的狂犬病毒的减毒活疫苗，其制备方法及其用途。该制备方法包括获得被绿色荧光蛋白（GFP）基因取代了 vsocs 基因的重组病毒，分离纯化 vsocs 基因缺失的病毒以获得减毒活疫苗。该疫苗可用于预防鱼类中的巨轮病毒感染。 展开▼

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公开/公告号WO2012037723A1

专利类型

公开/公告日2012-03-29

原文格式PDF

申请/专利权人 SUN YAT-SEN UNIVERSITY;JIA KUNTONG;GUO CHANGJUN;HE JIANGUO;HUANG ZHIJIAN;ZHANG YINGFEN;WENG SHAOPING;YANG LISHI;YANG XIAOBO;LIU DONG;
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申请/专利号WO2010CN77198

发明设计人 GUO CHANGJUN;HE JIANGUO;HUANG ZHIJIAN;ZHANG YINGFEN;WENG SHAOPING;YANG LISHI;YANG XIAOBO;LIU DONG;JIA KUNTONG;
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申请日2010-09-21

分类号A61K39/12;C12N7/01;A61P31/20;

国家 WO

入库时间 2022-08-21 17:17:03

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