首页> 外国专利> DERIVATIVES OF BENZOD ISOTHIAZOLES AS HISTONE DEACETYLASE INHIBITORS

DERIVATIVES OF BENZOD ISOTHIAZOLES AS HISTONE DEACETYLASE INHIBITORS

机译:苯并[D]异噻唑类衍生物作为组蛋白十足类抑制剂

摘要

The invention relates to derivatives of benzo[d]isothiazoles as histone deacetylase inhibitors, selected from among compounds of general formula (Ia) and (Ib) or one of the salts thereof, particularly one of the pharmaceutically acceptable salts thereof, or one of the corresponding solvates thereof. These compounds are histone deacetylase enzyme inhibitors and are suitable as pharmacologically active agents in a medicament for the treatment and/or prophylaxis of disorders or diseases associated to histone deacetylases. The invention also describes a process for obtaining the mentioned compounds and the pharmaceutical compositions containing them
机译:本发明涉及作为组蛋白脱乙酰基酶抑制剂的苯并[d]异噻唑衍生物,其选自通式(Ia)和(Ib)的化合物或其盐之一,特别是其药学上可接受的盐之一,或相应的溶剂化物。这些化合物是组蛋白脱乙酰基酶抑制剂,并且适合用作药物中的药理活性剂,用于治疗和/或预防与组蛋白脱乙酰基酶相关的病症或疾病。本发明还描述了获得所述化合物的方法和包含它们的药物组合物

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