METHOD FOR DIFFERENTIATING MUSCLE-DERIVED STEM CELLS USING BASIC FIBROBLAST GROWTH FACTOR(bFGF) AND NERVOUS SYSTEM DRUGS

摘要

PURPOSE: A method for differentiating muscle-derived stem cells into neural cells using bFGF of high concentration and neural system drugs is provided to obtain cell source for regenerating a central nervous system.;CONSTITUTION: A method for differentiating muscle-derived stem cells into neural cells comprises a step of using a material which induces muscle-derived stem cells into neural cells. The material is nervous system drug and bFGF(basic fibroblast growth factor). The muscle-derived stem cells are treated using 10-25ng of bFGF and 0.0625 mM to 4 mM of nervous system drug. The nervous system drug is ethosuximide, carbamazepine, valproic acid, galantamine, levodopa, or donepezil.;COPYRIGHT KIPO 2012