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Rhodanine derivatives exhibiting peroxisome proliferator-activated receptor activity

机译:罗丹宁衍生物表现出过氧化物酶体增殖物激活的受体活性

摘要

The present invention provides novel rhodanine derivatives person activating the peroxisome proliferator activated receptor PPAR in relates to . In the present invention, which acts as a PPAR activator beta - carboxy -ethyl- loader is non- derivative or a pharmaceutically acceptable salt thereof provided . Beta according to the present invention - carboxyethyl - rhodanine derivative may represent the prevention , improvement and therapeutic effects against diabetes and mediated by the PPAR by having a function to control the PPAR , high blood pressure , atherosclerosis , cardiovascular diseases , metabolic diseases there .
机译:本发明提供了新的激活过氧化物酶体增殖物激活受体PPAR的罗丹碱衍生物。在本发明中,其充当PPAR活化剂β-羧基-乙基-载体是非衍生物或其药学上可接受的盐。根据本发明的β-羧乙基-罗丹宁衍生物可以通过具有控制PPAR,高血压,动脉粥样硬化,心血管疾病,新陈代谢疾病的功能来代表针对糖尿病的预防,改善和治疗作用,并且由PPAR介导。

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