PREPARING METHOD OF GEL PASTE COMPOSITION FOR TREATMENT AN ULCER INCLUDING A HONEY AND GEL PASTE COMPOSITION FOR TREATMENT AN ULCER THEREBY

摘要

PURPOSE: A paste composition for ulcer treatment including honey and a manufacturing method thereof are provided to improve properties of cohesive property, transparency, sterilization, and storability. CONSTITUTION: A manufacturing method of paste composition for ulcer treatment comprises the following steps: manufacturing aqueous solution by dissolving biocompatible polymer in purified water(1 step); forming a gel state sheet by pouring aqueous solution into a tray(2 step); irradiating radiation in the aqueous solution(3 step); shattering the gel into pieces(4 step); and manufacturing paste by dissolving pulverized gel, honey, and preservative in the purified water(5 step). The biocompatible polymer is polyvinyl alcohol, polyvinyl pyrrolidone, synthetic high polymer of polyacrylic acid, polyethylene oxide, natural polymer of carrageenan, sodium carboxymethyl cellulose, gelatin, agar, alginate, or chitosan. In step 1, weight ratio of biocompatible polymer mixed in the purified water is 1 to 30 weight%. In step 3, the radiation is gamma-ray, ultraviolet ray, or electronic beam. An amount of the radiant exposure is 2-200 kGy.