A CHEMO-SENSITIZER COMPOSITION COMPRISING AMURENSIN G SHOWING POTENT SIRT1 ENZYME INHIBITOR FOR TREATING OR PREVENTING CANCER DISEASE

摘要

PURPOSE: in a kind of cancer chemotherapy sensitizer and composition of natural products isolation is provided to strong inhibition SIRT1 enzyme activations and to enhance cytotoxicity and cancer cell. ;CONSTITUTION: a kind of anticancer assistant composition contain the anti-mutually Ji Cancerous disease amurensin Vitis amurensis isolation extracts of system or its pharmacologically acceptable salt as active constituent. The extract is isolated with water, including purified water, methanol, butanol or solvent mixture in. Anticancer assistant composition contains amurensin G, pharmaceutically acceptable salt or Vitis amurensis extracts. Anticancer agent contains amurensin G, adriamycin, cyclophosphamide, 5-FU, amsacrine, taxol. ;The 2012 of copyright KIPO submissions