DEVICE FOR AUTOMATED SIMULTANEOUS isolation and purification of nucleic acids from biological samples MORE

摘要

The invention relates to biotechnology, molecular biology, microbiology and medicine and relates to a device for the simultaneous automated isolation and purification of nucleic acids from multiple biological samples. The constituent parts of the device are mounted on a rotating platform set of interchangeable modules, each of which contains all reagents needed for processing the biological sample, a motor compressor unit of air valves, the block forming air streams flow distribution of air streams, a heater block stirring mixtures blocks supply, the electronic control unit, with the housing cover and a locking mechanism. Each of the modules happens isolation and purification of nucleic acids from a biological sample. Moving the reaction mixtures within the modules is carried out during rotation of the platform, as well as excessive pressure supplied to the respective units through a valve system reservoirs. overpressure supply is via a compressor unit forming and air distribution unit. sample processing procedure carried inside the module, isolated from the external environment, which minimizes the risk of contamination and infection of personnel. The resulting purified nucleic acid preparations can be used directly for conducting hybridization, amplification and / or subsequent molecular genetic analyzes.