Microfluidic Module for Automated Isolation and Purification of Nucleic Acids from Biological Samples

摘要

A device for isolation and purification of nucleic acids from biological specimens using a microfluidic module comprising vessels with reagents, microchan-nels, and valves, which are required for movement of solutions and reaction mixtures within the module, was developed. The procedure is automated and completely excludes the contact of a researcher and a potentially pathogenic specimen. The obtained nucleic acid preparation can be immediately used in molecular-genetic analysis.