首页>
外国专利>
Process for crossed claisen condensation reactions promoted by lithium amide in liquid ammonia
Process for crossed claisen condensation reactions promoted by lithium amide in liquid ammonia
展开▼
机译:氨化锂在液氨中促进的交叉克莱森缩合反应的方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention provides a use of lithium amide in liquid ammonia as a base to produce an enolate from at least one ester starting material in a crossed Claisen condensation reaction, wherein at least one ester starting material is a -hydroxy ester. Also provided is a method of producing lithium amide in situ for use in a crossed Claisen condensation reaction, wherein lithium is added to liquid ammonia, followed by an electron transfer agent, as well as a method of carrying out a crossed Claisen condensation reaction using an ester starting material and a -hydroxy ester, using lithium amide in liquid ammonia produced in situ.
展开▼