Epithelial cell adhesion enhancer and allergy ameliorating, treating or preventing agent using the same

摘要

PROBLEM TO BE SOLVED: To compare with a synthetic steroid oral medicine, although it is generally familiar as an ion that is present as a food or in vivo and is not toxic to the living body within a physiological concentration range. Provided is a composition comprising a specific oligosaccharide and a divalent metal cation that is extremely safe and effective for ameliorating, treating or preventing allergy, or having a local inflammatory response. An agent for enhancing cell adhesion in epithelial cells, comprising 1-kestose and / or nystose and a divalent metal cation as active ingredients. According to the present invention, in addition to suppressing the destruction of the epithelial cell tight junction protein that causes the allergen to enter the body, the epithelial cell indirect cell indirect by repairing or promoting the formation of the epithelial cell tight junction protein Increases wearing and enables effective improvement, treatment and prevention of allergic symptoms.