EPITHELIAL CELL-CELL ADHESION ENHANCER AND AMELIORATING THERAPEUTIC OR PROPHYLACTIC AGENT FOR ALLERGIC DISEASES USING SAME

摘要

In general, it is extremely safe and effective to improve, treat or prevent allergies in comparison with synthetic steroids, even though they are used as foods or in vivo and contain familiar components as ions which are not toxic to living organisms within a physiological concentration range. Or a composition comprising a specific oligosaccharide and a divalent metal cation that is effective in a local inflammatory reaction. As an intercellular adhesion enhancer in epithelial cells, 1-cystose and / or nistissue and divalent metal cations are used as active ingredients. According to the present invention, not only the destruction of the tight junction protein between the epithelium that causes the invasion of the allergen into the body but also the restoration of the tight junction protein of the epithelium or the promotion of the formation, Effective treatment, prevention and prevention of symptoms of allergic diseases becomes possible.