Process for producing 1,2-phenylethane compounds using atom transfer radical coupling reaction

摘要

With the reaction of brief, in quite high yield, offer the method of being possible to produce 1,2- phenyl ethane based chemical compound. Under existing of transition metal complex, formula (i) Conversion 1 So the chemical compound which is displayed (Ra, displays the phenyl group of the hydrogen atom, or substitution or non substitution, Rb displays the hydrogen atom or the substituent, n displays integer 1 - 5, when n is 2 or more, Rb may be being identical, differing, connecting mutually, to form ring is possible, X displays the halogen atom.)The coupling reacting, formula (ii) Conversion 2 So it is production method of the 1,2- phenyl ethane based chemical compound which produces the chemical compound which is displayed.