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METHOD FOR PRODUCING 1,2-PHENYLETHANE COMPOUND USING ATOM TRANSFER RADICAL COUPLING REACTION
METHOD FOR PRODUCING 1,2-PHENYLETHANE COMPOUND USING ATOM TRANSFER RADICAL COUPLING REACTION
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机译:原子转移自由基偶联反应制备1,2-苯乙烷的方法
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摘要
An object of the present invention is to provide a method capable of producing a 1,2-phenylethane compound with extremely high yield in a short amount of tirae. Disclosed is a method for producing a 1,2-phenylethane compound, which comprises subjecting a compound represented by formula (I): wherein Ra represents a hydrogen atom or a substituted or unsubstitutsd phenyl group; Rb represents a hydrogen atom or a substituent; n represents an integer of 1 to 5 and when n is 2 or more, Rb may be the same or different, or may be combined with each other to form a ring; and X represents a halogen atom; to a coupling reaction in the presence of a transition metal complex to produce a compound represented by formula (II):
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