PROBLEM TO BE SOLVED: To provide a medicine generally improving a depressed state or the subjective mental condition of the depression by a POMS (Profile of Mode States) evaluation.;SOLUTION: This improving agent contains an organic germanium compound expressed by formula (1) [wherein, R1 to R3 are each H, the same or different lower alkyl such as methyl, ethyl, etc., or a substituted or non-substitute phenyl; and X is hydroxy, a group expressed by O-a lower alkyl, amino or a salt expressed by OY (wherein, Y is a metal such as sodium, potassium, etc., or a compound having a basic group such as lysozyme, a basic amino acid or the like) respectively].;COPYRIGHT: (C)2008,JPO&INPIT
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