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Furanocoumarin removal from grapefruit juice by edible fungal hyphae

机译:食用菌丝从葡萄柚汁中去除呋喃香豆素

摘要

A method for removing furanocoumarins from a liquid includes the steps of incubating the liquid with fungal hyphae for at least about two hours and removing the hyphae from the liquid by a filtration step. The furanocoumarins can be recovered from the hyphae using methods within the ordinary skill in the art. The method is useful for the removal of furanocoumarins from furanocoumarin-containing citrus juice so that the juice can be safely consumed by humans taking drugs that are metabolized by P450 CYP3A, which is the enzyme responsible for the metabolism of many widely-prescribed medications.
机译:从液体中除去呋喃香豆素的方法包括以下步骤:将液体与真菌菌丝一起孵育至少约两个小时,并通过过滤步骤从液体中除去菌丝。可以使用本领域普通技术人员的方法从菌丝中回收呋喃香豆素。该方法可用于从含呋喃香豆素的柑桔汁中去除呋喃香豆素,从而使服用该药的人可以安全地食用该果汁,该药物是通过P450 CYP3A代谢的,该酶是许多广泛处方药物的代谢酶。

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