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solid pharmaceutical composition, and method for improving the dissolution of an active ingredient from a solid pharmaceutical composition

机译:固体药物组合物,以及用于改善活性成分从固体药物组合物中溶解的方法

摘要

"SOLID PHARMACEUTICAL COMPOSITION AND METHOD FOR IMPROVING DISSOLUTION OF AN ACTIVE INGREDIENT OF A SOLID PHARMACEUTICAL COMPOSITION". A pharmaceutical composition is described containing a low melting oil / fat-like substance, which is improved in drug dissolution property and has excellent dissolution properties and stability. Specifically, a pharmaceutical composition is described comprising a pharmacologically active ingredient, a low melting oil / fat-like substance and a low viscosity binder. Also described is a method for improving the elution of the pharmacologically active ingredient from a solid pharmaceutical composition comprising the pharmacologically active ingredient and the low melting oil / fat-like substance, characterized by using a low viscosity binder.
机译:“固体药物组合物和用于改善固体药物组合物活性成分溶解的方法”。描述了包含低熔点油/类脂肪物质的药物组合物,其改善了药物溶出性并且具有优异的溶出性和稳定性。具体地,描述了包含药理活性成分,低熔点油/类脂肪物质和低粘度粘合剂的药物组合物。还描述了一种改善药理活性成分从包含药理活性成分和低熔点油/脂样物质的固体药物组合物中洗脱的方法,其特征在于使用低粘度粘合剂。

著录项

  • 公开/公告号BRPI0716030A2

    专利类型

  • 公开/公告日2013-07-30

    原文格式PDF

  • 申请/专利权人 TAKEDA PHARMACEUTICAL COMPANY LIMITED;

    申请/专利号BR2007PI16030

  • 发明设计人 YUKIHIRO NOMURA;MUNEO NONOMURA;

    申请日2007-08-09

  • 分类号A61K47/34;A61K9/20;A61K31/4245;A61K47/38;

  • 国家 BR

  • 入库时间 2022-08-21 16:42:15

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