Crystalline hydrochloride of 1 - (4 - metoxibutil) - N - (2-methylpropyl) - N - (3S, 5R) - 5 - (4 - (3 - ilcarbonil) piperidin yl - 1h-benzimidazol-2 - carboxamide,Renin Inhibitor, Pharmaceutical Composition and use in the prophylaxis or treatment of a Circulatory disease, renal disease and Hypertension.

摘要

p CRYSTALINE FORM OF CHLORHYDRATE 1- (4-METOXIBUTIL) -N- (2-METHYLPROPIL) -N- (3S, 5R) -5 (MORFOLI N-4-I READ RBONI I) PI PERID IN 3-I 1] -1 H-BENCIMIDAZOL-2-CARBOXA MEASURES THAT IT IS ATTACHING A DIFFACTION PATTERN OF POWDER-X-RAYS THAT SHOW CHARACTERIC SPACES (S) OF INTERPLANE SPACES (D) OF 26.43 plusmn; 0.2, 7.62 plusmn; 0.2 and 4.32 plusmn; 0.2 ANGSTROMS; PHARMACEacute; UTICA COMPOSITION; AND USE IN THE PROPHYLAXIS OR TREATMENT OF A CIRCULATORY DISEASE, RENAL DISEASE AND HYPERTENSION. /p