首页> 外国专利> Hydrochloride Crystal of 1 - (4 - metoxiobutil) - N - (2-methylpropyl) - N - ((3S, 5R) - (4 - (3 - ilcarbonil) piperidin yl) - 2 - (11h benzimidazole carboxamide has Inhibitory activity of renin

Hydrochloride Crystal of 1 - (4 - metoxiobutil) - N - (2-methylpropyl) - N - ((3S, 5R) - (4 - (3 - ilcarbonil) piperidin yl) - 2 - (11h benzimidazole carboxamide has Inhibitory activity of renin

机译:1-(4--甲氧噻菌胺)-N-(2-甲基丙基)-N-((3S,5R)-(4-(3-伊卡培尔)哌啶基)-2-(11h苯并咪唑羧酰胺的盐酸盐晶体具有抑制活性肾素

摘要

Describes a hydrochloride Crystal of 1 - (4 - metoxibutil) - N - (2 - metiipropil) - N - [(3S, 5R) - 5 - ((4 - ilcarbonil piperidin - II) 3] - 1h-benzimidazol-2 - carboxamide which has excellent Inhibitory activity of renin that is useful as a Therapeutic agent for Conservative or other types of dis Function of organs and the like, that are derived from high blood pressure and Hypertension.The Crystal of hydrochloride of 1 - (4 - metoxibutil) - N - (2 - metiipropil) - N - [(3S, 5R) - 5 - (morfoiin - 4 - 3 - ilcarbonil) piperidin yl] - 1h-benzimidazol-2 - carboxamide has a pattern of x-ray diffraction Powder, where the Lattice spacing (d) x-ray diffraction pattern of dust, Tien And characteristic Peaks that appear in the vicinity of 26.43 (0.2, 0.2 and 7.62 + 4.32 (0.2 angstroms.
机译:描述1-(4--甲氧西丁(Metoxibutil))-N-(2--异丙基异丙醇)-N-[(3S,5R)-5-((4-伊卡培尔哌啶-II)3]-1h-苯并咪唑-2-的盐酸盐晶体具有优异的肾素抑制活性的羧酰胺,可用作高血压或高血压引起的器官或其他器官功能失调等的治疗剂.1-(4--甲氧西util )-N-(2-甲丙腈)-N-[((3S,5R)-5-(吗啡-4-3-ilcarbil)哌啶基]]-1h-苯并咪唑-2-甲酰胺具有X射线衍射图谱,其中尘埃的格子间距(d)X射线衍射图,层和特征峰出现在26.43(0.2,0.2和7.62 + 4.32(0.2埃)附近。

著录项

  • 公开/公告号CO6670573A2

    专利类型

  • 公开/公告日2013-05-15

    原文格式PDF

  • 申请/专利权人 TAKEDA PHARMACEUTICAL COMPANY LIMITED;

    申请/专利号CO20130006575

  • 发明设计人 KITAYAMA MASATO;

    申请日2013-01-15

  • 分类号A61K31/5377;A61P9;A61P9/12;A61P13/12;A61P43;C07D401/12;

  • 国家 CO

  • 入库时间 2022-08-21 16:42:07

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