hydrochloride crystal, drug, methods for the prophylaxis or treatment of a disease and hypertension and / or various organ disorders, and use of the crystal. a crystal of 1- (4-methoxybutyl) -N- (2-methylpropyl) -N- [(3s, 5r) -5- (morpholin-4-ylcarbonyl) piperidin-3-yl] -1h- benzimidazole-2-carboxamide which has excellent renin inhibiting activity and which is useful as a preventative or therapeutic agent for types of organ dysfunction and the like arising from high blood pressure and hypertension. 1- (4-methoxybutyl) -n- (2-methylpropyl) -n - [(3s, 5r) -5- (morpholin-4-ylcarbonyl) piperidin-3-yl] -1h-benzimidazol-hydrochloride crystal 2-carboxamide has a powder x-ray diffraction pattern in which the crystalline reticulum spacing of (x) powder x-ray diffraction has characteristic peaks appearing at the vicinity of 26.43 sym 0.2, 7 .62 sym 0.2 and 4.32 sym 0.2 angstroms.
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