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PHARMACEUTICAL COMPOSITION 'MICEPHOSPHONE' PROMOTING THE SUPPORTING TISSUE

机译:药用组合物“ MICEPHOSPHONE”促进组织的发展

摘要

The invention relates to the field of medicine and pharmacy, in particular to the creation of a pharmaceutical composition in the form of a suspension for the prevention and treatment of disorders of the physiological and reparative regeneration of tissues of the musculoskeletal system - bone tissue and articular cartilage, in particular for the treatment of osteoporosis. The pharmaceutical composition for the prevention and treatment of disorders of the physiological and reparative regeneration of tissues of the musculoskeletal system - bone tissue and articular cartilage, includes dimephosphon (dimethyloxobutylphosphonyl dimethylate), calcium carbonate in the form of the substance "Calcium carbonate and magnesium micellate", sodium polysaccharide-hyalurium sodium salt in the following ratio of components, wt.%: The pharmaceutical composition as an auxiliary substance contains alcohol, nipagin, fructose. Studies have shown that the proposed pharmaceutical compositions have a pronounced specific pharmacological effect, exhibiting a reparative-regenerative effect in relation to the bone tissue of animals, and do not have a pronounced general toxic effect at various doses and routes of entry into the body of experimental animals. Compositions do not have an irritating effect, no sensitizing effect was found. The proposed pharmaceutical compositions are effective and safe and can be used for the prevention and treatment of disorders of the physiological and reparative regeneration of tissues of the musculoskeletal system, including patients with diabetes mellitus.
机译:本发明涉及医学和药学领域,特别涉及以悬浮液形式的药物组合物的制备,该悬浮液用于预防和治疗肌肉骨骼系统的组织的生理性和修复性再生障碍-骨组织和关节软骨,特别是用于治疗骨质疏松症。预防和治疗肌肉骨骼系统组织的生理和修复性再生障碍的药物组合物-骨组织和关节软骨,包括二甲phosph磷(二甲基氧代丁基膦酰基二甲基甲酸酯),形式为“碳酸钙和胶束镁的碳酸钙” “,多糖钠-透明质酸钠盐,按以下组分的重量百分比计:作为辅助物质的药物组合物包含醇,尼泊金,果糖。研究表明,所提出的药物组合物具有明显的特定药理作用,相对于动物的骨组织具有修复-再生作用,并且在各种剂量和进入人体的途径中均没有明显的一般毒性作用。实验动物。组合物不具有刺激作用,未发现致敏作用。所提出的药物组合物是有效和安全的,并且可以用于预防和治疗肌肉骨骼系统(包括糖尿病患者)的组织的生理性和修复性再生障碍。

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