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7-azaindole derivatives as selective 11- beta-hydroxysteroid dehydrogenase type 1 inhibitors
7-azaindole derivatives as selective 11- beta-hydroxysteroid dehydrogenase type 1 inhibitors
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机译:7-氮杂吲哚衍生物作为选择性的11-β-羟类固醇脱氢酶1型抑制剂
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摘要
The present invention relates to 7-azaindole derivatives of formula I as selective inhibitors of the enzyme 11-beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD-1) and the use of such compounds for the treatment and prevention of metabolic syndrome, diabetes, insulin resistance, obesity, lipid disorders, glaucoma, osteoporosis, cognitive disorders, anxiety, depression, immune disorders, hypertension and other diseases and conditions.
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