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A dosage form comprising tapentadol and an opioid antagonist
A dosage form comprising tapentadol and an opioid antagonist
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机译:包含他喷他多和阿片样物质拮抗剂的剂型
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ABSTRACT - 592437 Disclosed herein is a dosage form comprising: at least one form of tapentadol, at least one opioid antagonist, and a second analgesic, wherein the said opioid antagonist improves the efficacy and or reduces the side effects of tapentadol, and wherein said opioid antagonist is selected from the group consisting of naloxone, naltrexone, nalmefene, methylnaltrexone, nalide, nalmexone, nalorphine, naluphine, haloperidol, promethazine, fluphenazine, perphenazine, levomepromazine, thioridazine, perazine, chlorpromazine, chlorprothixine, zuclopentixol, flupentixol, prothipendyl, zotepine, benperidol, pipamperone, melperone and bromperidol.
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