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Ligand-based drug design: I. conformational studies of GBR 12909 analogs as cocaine antagonists; II. Three-dimensional-QSAR studies of salvinorin A analogs as kappa opioid agonists

机译：基于配体的药物设计：I. GBR 12909类似物作为可卡因拮抗剂的构象研究；二。 Salvinorin A类似物作为κ阿片类激动剂的三维QSAR研究

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作者
Pandit, Deepangi;
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作者单位

New Jersey Institute of Technology;

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授予单位 New Jersey Institute of Technology;
学科
学位 Ph.D.
年度 2007
页码 115 p.
总页数 115
原文格式 PDF
正文语种 eng
中图分类
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入库时间 2022-08-17 11:55:19

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专利

1. A combined ligand-based and target-based drug design approach for G-protein coupled receptors: application to salvinorin A, a selective kappa opioid receptor agonist [J] . Singh N, Cheve G, Ferguson DM, Journal of Computer-Aided Molecular Design . 2006,第7a8期

机译：G蛋白偶联受体的基于配体和靶标的组合药物设计方法：应用于salvinorin A（选择性κ阿片受体激动剂）的应用
2. A combined ligand-based and target-based drug design approach for G-protein coupled receptors: application to salvinorin A, a selective kappa opioid receptor agonist [J] . Nidhi Singh, Gwénaël Chevé, David M. Ferguson, Journal of Computer-Aided Molecular Design . 2006,第7a8期

机译：G蛋白偶联受体的基于配体和靶标的联合药物设计方法：应用于salvinorin A（选择性κ阿片受体激动剂）的应用
3. N-methylacetamide analog of salvinorin A: a highly potent and selective kappa-opioid receptor agonist with oral efficacy. [J] . Beguin C, Potter DN, Dinieri JA, The Journal of Pharmacology and Experimental Therapeutics: Official Publication of the American Society for Pharmacology and Experimental Therapeutics . 2008,第1期

机译：Salvinorin A的N-甲基乙酰胺类似物：一种高效且选择性的κ阿片受体激动剂，具有口服功效。
4. Synthesis and pharmacological activity of Dmt-Tic analogs with highly potent agonist and antagonist/agonist opioid activity [C] . Remo Guerrini, Gianfranco Balboni, Daniela Girolamo Calo, the International Peptide Symposium . 2001

机译：具有高效激动剂和拮抗剂/激动剂阿片类能活性DMT-TIC类似物的合成与药理活性
5. Design and Synthesis of Cyclic Analogs of the Kappa Opioid Receptor Antagonist Arodyn [D] . Gisemba, Solomon Aguta. 2018

机译：κ阿片受体拮抗剂Arodyn环状类似物的设计与合成
6. Salvinorin A analogs and other kappa opioid receptor compounds as treatments for cocaine abuse [O] . Bronwyn M Kivell, Amy WM Ewald, Thomas E Prisinzano -1

机译：Salvinorin A类似物和其他Kappa阿片受体化合物可卡因滥用的治疗方法
7. Salvinorin A Analogs and Other Kappa-Opioid Receptor Compounds as Treatments for Cocaine Abuse [O] . Bronwyn M. Kivell, Amy W.M. Ewald, Thomas E. Prisinzano 2014

机译：Salvinorin A类似物和其他Kappa-Apioid受体化合物作为可卡因滥用的处理

Ligand-based drug design: I. conformational studies of GBR 12909 analogs as cocaine antagonists; II. Three-dimensional-QSAR studies of salvinorin A analogs as kappa opioid agonists

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