Transcriptional signature in the blood of active versus Latent Mycobacterium tuberculosis infection

摘要

It relates to a method for Detecting an active infection by Mycobacterium tuberculosis that is Latent, asymptomatic comprising) to obtain a Data Set of gene expression of patients with Latent Infection and asymptomatic by Mycobacterium tuberculosis; (b) classify the conj Both gene expression data obtained in STEP (a) into Genetic modules associated with aInfection by Mycobacterium tuberculosis; (c) to compare the gene expression Data Set for a patient not classified with the genetic modules described in (b), where an increase or decrease in the whole gene expression indicates an active infection by Mycobacterium t Uberculosis instead of a Latent Infection and asymptomatic