MTOR cinasa inhibitors for tumor and disease markers related to mTOR / PI3K / Akt trajectories

摘要

It refers to the compound in 3,4-dihydropyridine [2,3-b] Pyridine-2 (1H) - formula (II), wherein R1 is isomerized or isomerized, such as pyridine, pyridine, pyridine, 1H pyridine [2,3-b] pyridine, etc.; R2 is h, hydrocarbon (C1-C8),Cyclopropyl (C3-C10),Among other things, isocyclohexane; R3 is h or tar (C1-C8). - [1 - [1 - [2]] - 1,4 - [1,4] - 1 - [(8-isopropyl-7-oxo-5,6,7,8-tetrahydropyridine [2,3-b] pyridine-2-il) - 4-methylpyridine; Someone else He also mentioned a pharmaceutical composer These compounds are enzyme inhibitors and are useful in the treatment of cancer, flammable screws, and immunology.