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Procedure for determination of genetic predisposition to Parkinson's disease.

机译:确定帕金森氏病遗传易感性的程序。

摘要

Procedure for determination of genetic predisposition to Parkinson's disease. # The present invention provides a method for predicting the predisposition of an individual to suffer from Parkinson's disease (PD) from a blood sample isolated from said individual. Said method comprises the combined use of 36 novel SNPs with ability to predict the onset pre-clinically complex PD. Similarly, the present invention provides a method comprising the use of a digenic combination of SNPs loci SIL1 x CHR6, which gives these carriers increased risk of Parkinson's disease.
机译:确定帕金森氏病遗传易感性的程序。本发明提供了一种用于根据从所述个体分离的血液样本中预测该个体易患帕金森氏病(PD)的倾向的方法。所述方法包括结合使用36种能够预测临床前复杂PD发作的新型SNP。类似地,本发明提供了一种方法,该方法包括使用SNP位点SIL1×CHR6的双基因组合,其使这些携带者增加了帕金森氏病的风险。

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