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GENETICALLY ENHANCED CYANOBACTERIA LACKING FUNCTIONAL GENES CONFERRING BIOCIDE RESISTANCE FOR THE PRODUCTION OF CHEMICAL COMPOUNDS
GENETICALLY ENHANCED CYANOBACTERIA LACKING FUNCTIONAL GENES CONFERRING BIOCIDE RESISTANCE FOR THE PRODUCTION OF CHEMICAL COMPOUNDS
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机译:基因缺失的功能增强基因的增强型蓝细菌,可产生化学化合物
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摘要
One embodiment of the invention provides a genetically enhanced cyanobacterium producing a first chemical compound comprising: -a genetically enhanced genome with a first gene inactivation in a first essential or conditionally essential gene of the cyanobacterium, and -a first extrachromosomal plasmid harboring the first essential or conditionally essential gene and at least one first production gene for production of the first chemical compound, -wherein the cyanobacterium lacks a functional gene conferring biocide resistance. These cyanobacteria can produce a first valuable chemical compound in long-term cultures without the need to employ genes conferring biocide resistance.
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