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METHOD FOR DETERMINING THE ACTIVITY OF THE LYSOPHOSPHATIDIC ACID (LPA) RECEPTOR LPA1

机译：测定糖脂酸（LPA）受体LPA1活性的方法

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摘要

The invention relates in particular to a method for determining, in vitro, the specific activity of the LPA1 receptor by measuring the expression of the HBEGF and CXCL3 markers, in particular for determining, in vitro, the modulatory activity of a compound specifically with respect to the LPA1 receptor, in particular in the context of monitoring the efficacy of a therapeutic compound specifically targeting the LPA1 receptor.

机译：本发明尤其涉及一种通过测量HBEGF和CXCL3标志物的表达来体外测定LPA1受体比活性的方法，特别是用于体外测定的方法。，特别是在监测特异性靶向LPA1受体的治疗化合物的功效的情况下，化合物相对于LPA1受体的调节活性。 展开▼

著录项

公开/公告号WO2013121146A1

专利类型

公开/公告日2013-08-22

原文格式PDF

申请/专利权人 UNIVERSITE CLAUDE BERNARD LYON I;HOSPICES CIVILS DE LYON;
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申请/专利号WO2013FR50295

发明设计人 PEYRUCHAUD OLIVIER;DAVID MARION;CLEZARDIN PHILIPPE;
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申请日2013-02-14

分类号C12Q1/68;

国家 WO

入库时间 2022-08-21 16:31:20

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