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DRUG BALLOON BASED ON HYDROGEN-BOND INTERACTION AND COATING METHOD THEREFOR

机译:基于氢键相互作用的药物球及其涂层方法

摘要

Disclosed is a drug coated balloon based on hydrogen-bond interaction and the coating method therefor. The balloon comprises a balloon surface and a drug layer containing an active drug. The balloon surface carries hydrophilic groups as a result of treatment or modification; there is hydrogen-bond interaction between the balloon surface and the drug layer. The hydrogen-bond interaction increases the binding force between the drug layer and the balloon surface, thus ensuring the extensibility of the coated layer and favoring the loading of a drug on the balloon surface.
机译:本发明公开了一种基于氢键相互作用的药物涂覆球囊及其涂覆方法。球囊包括球囊表面和包含活性药物的药物层。处理或修饰后,球囊表面带有亲水基团;球囊表面和药物层之间存在氢键相互作用。氢键相互作用增加了药物层与球囊表面之间的结合力,从而确保了涂层的可延展性并有利于药物在球囊表面上的负载。

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