Oral solid preparation composition containing silymarin using membrane emulsification technique, and its production method

摘要

This invention relates to the silymarin oral solid preparation composition which improved the solubility and bioavailability of the silymarin using the membrane emulsification method. The present invention improves the poor solubility and bioavailability of poorly soluble silymarin and at the same time, the complexity of the preparation method, the use of organic solvents, the large volume of the formulation required for single administration, and the low compliance with the medication It provides a silymarin oral solid preparation composition that can be solved and a method for producing the same.