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METHOD AND APPARATUS FOR EXTRACTING CORE PROTEIN NETWORK FOR DISEASE RESEARCH

机译:用于疾病研究的提取核心蛋白质网络的方法和装置

摘要

In order to solve the aforementioned technical problem, the key for disease study in accordance with one embodiment of the present invention Network protein extraction method, comprising: receiving data for a protein interaction, the received detecting a protein interaction data related to a specific disease of the data, the detected protein-protein interaction between the information contained in the correlation data on the basis of, generating a first protein network, tree (tree) generating a second network of protein structure, the second network to a particular protein protein protein in the first network to the root (root) node protein protein calculating a weight (weight) of the edge (edge) between nodes included in the, in the protein network, and the second, to remove one or more of the specific edge generating at least two sub-networks, and each of the sub- recalculating the weights of the edges in the network, by each sub-network, the sum of the re-calculated weight, and a step of determining each of the power of the sub-networks to the network. ;
机译:为了解决上述技术问题,根据本发明的一个实施例的疾病研究的关键是网络蛋白质提取方法,包括:接收蛋白质相互作用的数据,所接收的检测与特定疾病有关的蛋白质相互作用数据在数据的基础上,检测到的蛋白质间相互作用的信息包含在相关数据的基础上,生成第一蛋白质网络,树(tree)生成第二蛋白质结构网络,第二网络将特定的蛋白质蛋白质第一个网络到根(根)节点蛋白蛋白质,计算该蛋白质网络中包含的节点之间的边缘(边缘)的权重(权重),第二个网络去除一个或多个在至少两个子网络,每个子网络通过每个子网络,重新计算的权重之和和一个st来重新计算网络中边缘的权重ep确定每个子网对网络的功率。 ;

著录项

  • 公开/公告号KR101274144B1

    专利类型

  • 公开/公告日2013-06-13

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20110099175

  • 发明设计人 유석종;

    申请日2011-09-29

  • 分类号G06F19/10;

  • 国家 KR

  • 入库时间 2022-08-21 16:25:00

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