Enviornmentally synthetic method for 2,3-dihydroquinazolinone derivatives and their spirooxindole derivatives

摘要

The present invention is 2,3-dihydro-quinazolinyl derivative and that his spiro Oaks on environmentally friendly method for the synthesis of indole derivatives, a variety of amines and aldehydes Benz moved TOEIC anhydride in the presence of a catalyst mindayi acetate ethylene diamine in water solvent (isatoic anhydride) can be reacted to synthesize the 2,3-dihydro-quinazolinyl derivative, also reacted with moving Toeic anhydride (isatoic anhydride) with a variety of amines in the presence of a catalyst few moving tinryu ethylenediamine mindayi acetate in water solvent dihydro-quinazolinyl may be synthesized biologically interesting spiro Oaks indole derivatives having a non-skeleton, it is possible to synthesize the compound as a simpler, environmentally friendly with a high yield via the synthetic method, it can be usefully applied to large-scale synthesis .