首页> 外国专利> METHOD OF MANUFACTURING PHARMACEUTICAL PRODUCT, CONTAINING CITRIC ACID, MAGNESIUM OXIDE, POTASSIUM BICARBONATE AND SODIUM PICOSULFATE, PHARMACEUTICAL COMPOSITIONS, CONTAINING THUS OBTAINED GRANULES AND INTERMEDIATE COMPOUND

METHOD OF MANUFACTURING PHARMACEUTICAL PRODUCT, CONTAINING CITRIC ACID, MAGNESIUM OXIDE, POTASSIUM BICARBONATE AND SODIUM PICOSULFATE, PHARMACEUTICAL COMPOSITIONS, CONTAINING THUS OBTAINED GRANULES AND INTERMEDIATE COMPOUND

机译:制造医药产品,包含柠檬酸,氧化镁,碳酸氢二钾钾和二十二碳酸钠,药物成分,包含上述颗粒和中间化合物的方法

摘要

FIELD: medicine, pharmaceutics.;SUBSTANCE: invention relates to method of manufacturing compositions, containing potassium bicarbonate and sodium picosulfate, which includes stage of application by spraying sodium picosulfate solution on potassium bicarbonate and drying of said salts with formation of granules, containing sodium picosulfate layer on potassium bicarbonate core. Invention also relates to composition, suitable for obtaining composition, which possesses laxative action, which contains granules, including sodium picosulfate layer, applied on potassium bicarbonate core. Invention also relates to composition, possessing laxative action, and to method of its obtaining, which contains granules of homogeneous mixture of citric acid, magnesium oxide, potassium bicarbonate and sodium picosulfate, and possibly sodium saccharin and/or orange flavouring agent, with granules containing sodium picosulfate, applied on potassium bicarbonate core.;EFFECT: invention is aimed at obtaining composition, which can be used for emptying of bowels before X-ray examination, endoscopy or surgery, which is homogeneous and possesses improved characteristics.;34 cl, 2 dwg, 3 ex
机译:包含碳酸氢钾和picosulfate钠的组合物的制备方法技术领域本发明涉及包含碳酸氢钾和picosulfate钠的组合物的制造方法,其包括通过将picosulfate硫酸钠溶液喷在碳酸氢钾上并干燥所述盐并形成颗粒的方法来形成包含picosulfate钠的颗粒的步骤。碳酸氢钾核心上的金属层。本发明还涉及适合获得具有泻药作用的组合物的组合物,该组合物包含施于碳酸氢钾核芯上的颗粒,包括微硫酸钠层。本发明还涉及具有泻药作用的组合物及其获得方法,该组合物包含柠檬酸,氧化镁,碳酸氢钾和苦味酸钠的均相混合物的颗粒,以及糖精钠和/或橙色调味剂,其中含有皮硫酸氢钠,应用于碳酸氢钾核心。效果:本发明旨在获得一种组合物,该组合物可用于X射线检查,内窥镜检查或手术前排空肠,其成分均一并具有改善的特性。; 34 cl,2 dwg,3 ex

著录项

  • 公开/公告号RU2473332C2

    专利类型

  • 公开/公告日2013-01-27

    原文格式PDF

  • 申请/专利权人 FERRING INTERNEHSHNL SENTER S.A.;

    申请/专利号RU20100112483

  • 发明设计人 KSU KHAJDZHUN (CN);DJAO TEDZHUN (CN);

    申请日2008-10-10

  • 分类号A61K9/16;A61K33/08;A61K31/194;A61P1/10;

  • 国家 RU

  • 入库时间 2022-08-21 16:23:14

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