It makes the ranitidine or more which are chosen from the production mannered null magnesium hydroxide

摘要

PROBLEM TO BE SOLVED: To provide a solid pharmaceutical formulation containing ranitidine that controls discoloration of the ranitidine, and a method for producing a ranitidine-supporting particle to be blended with the formulation.;SOLUTION: The solid pharmaceutical formulation containing ranitidine is characterized in that it has acid-controlling power larger than 200 mL which is determined by the acid-controlling power testing method according to the fifteenth Revision of Japanese Pharmacopoeia and that it contains the ranitidine-supporting particle which supports the ranitidine on an inorganic compound containing magnesium and/or calcium having a magnesium and/or calcium content of 20 mass% or higher.;COPYRIGHT: (C)2010,JPO&INPIT