Their use in the production of polyunsaturated fatty acids and Δ9 elongase mutant

摘要

Linoleic acid [18: 2, LA] to eicosadienoic acid: the [20 2, EDA], and / or α- linolenic acid [18: 3, ALA] eicosatrienoic acid: to convert [20 3, ETrA] have the ability, mutation Δ9 elongase is disclosed herein. An isolated nucleic acid fragment encoding a mutant Δ9 elongase, and recombinant constructs comprising such fragments are also in oleaginous yeast in using these mutations Δ9 elongase long chain polyunsaturated fatty acid [ "PUFA It is disclosed, along with methods for creating ".