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首页> 外文期刊>Diabetes >Remodeling of Retinal Fatty Acids in an Animal Model of Diabetes: A Decrease in Long-Chain Polyunsaturated Fatty Acids Is Associated With a Decrease in Fatty Acid Elongases Elov12 and Elov14
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Remodeling of Retinal Fatty Acids in an Animal Model of Diabetes: A Decrease in Long-Chain Polyunsaturated Fatty Acids Is Associated With a Decrease in Fatty Acid Elongases Elov12 and Elov14

机译：糖尿病动物模型中视网膜脂肪酸的重塑：长链多不饱和脂肪酸的减少与脂肪酸延长酶Elov12和Elov14的减少有关

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摘要

The results of the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications cohort study revealed a strong association between dyslipidemia and the development of diabetic retinopathy. However, there are no experimental data on retinal fatty acid metabolism in diabetes. This study determined retinal-specific fatty acid metabolism in control and diabetic animals.
机译：糖尿病控制与并发症试验/糖尿病干预与并发症流行病学队列研究的结果表明，血脂异常与糖尿病性视网膜病变的发展之间存在密切的联系。但是，尚无关于糖尿病中视网膜脂肪酸代谢的实验数据。这项研究确定了对照动物和糖尿病动物的视网膜特异性脂肪酸代谢。

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  • 来源
    《Diabetes》 |2010年第1期|p.219-227|共9页
  • 作者

    Maria Tikhonenko Todd A Lydic Yun Wang Weiqin Chen Madalina Opreanu Andrew Sochacki Kelly M McSorley Rebecca L Renis Timothy Kern Donald B Jump Gavin E Reid Julia V Busik;

  • 作者单位

    Maria Tikhonenko,1 Todd A. Lydie,1 Yun Wang,2 Weiqin Chen,3 Madalina Opreanu,1,4 Andrew Sochacki,1 Kelly M. McSorley,1 Rebecca L. Renis,5 Timothy Kern,6 Donald B. Jump,7 Gavin E. Reid,5,8 and Julia V. Busik1From the 1 Department of Physiology, Miclugan State University, East Lansing, Michigan, 2 GTx, Memphis, Tennessee, the 3 Department of Medicine. Baylor College of Medicine. Houston, Texas, the 4 Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, the 5 Department of Chemistry. Michigan Stale University, East Lansing, Michigan, the "Department of Medicine, Division of Endocrinology. Case Western Reserve University. Cleveland, Ohio, the rLinns Pauling Institute, Oregon State University, Corvallis. Oregon: mid the 8 Department of Biochemistry and Molecular Biology. Michigan State University, East Lansing. Michigan.Corresponding author: Julia V. Busik. busikCninsu.edu.Received 4 June 2009 and accepted 9 September 2009. Published altead of print at http://diabetes.diabeles.journals.org on 29 October 2009. DOI: 10.2337/db09-0728.M.T. and T.A.L. contributed equally to this work.© 2010 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit. and tile work is not altered. See http://creativecommous.org/licenses/by -nc-nd/8.0/ for details.The costs of publication of this article were defrayed in pari by the payment of paye charges. This article must therefore be hereby marked "advertisement" in accordance with IS U.S.C. Section 1734 solely to indicate this fuel.,;

  • 收录信息 美国《科学引文索引》(SCI);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
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  • 入库时间 2022-08-17 13:45:38

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