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Apparatus and method for characterizing blood and red blood cells by erythrocyte membrane vulnerability quantification

机译:通过红细胞膜易损性定量表征血液和红细胞的装置和方法

摘要

By quantifying the quality degradation erythrocytes stored individually (RBC) units, assignment of each of these, the present disclosure, which can yield information to patient compliance, and improving the decision on the use, I will explain the related apparatus and method. How to use this device and shows relative survival rate of the units in any particular, the validity, ie the expected and, in accordance with clinical implementation. When to which, and the decision of whether to use the transfusion of a particular patient unit number, which results in the actual data of RBC quality clinician. Furthermore, by developing this test through the supply chain, the distribution plan, and can improve the determination of inventory management. Results of the mass, by accumulating a mathematical analysis of that data and other relevant, an important aspect of this test system, it is possible to optimize the algorithm. Thereby, it is possible to characterize the test results after each meaningfully as possible. At the same time and on the application of quality control of blood, major technology in the "quantification of RBC vulnerability through the calculation and analysis of optical and subsequent hemolysis induced by stress", the present invention provides a wide range of applications, such as diagnosis of disease is possible. Apparatus for quantifying the quality degradation (RBC) storage of units each comprise a calculation unit hemolytic unit, and optical analysis unit. Similarly, hemolysis step, the optical analysis stage, and related methods for quantifying the quality degradation (RBC) storage of the unit herein includes a calculation step. [Selection Figure Figure 4
机译:通过量化可以单独存储的质量降解红细胞(RBC)单元,每个单元的分配(本公开可以产生患者依从性的信息)以及改进使用的决策,我将说明相关的装置和方法。如何使用此设备,并根据临床实施情况具体显示单位的相对存活率,有效性(即预期)。何时进行输血,以及是否使用特定患者单位输血的决定,这导致了RBC质量临床医生的实际数据。此外,通过开发此测试通过供应链,分配计划,并可以改善库存管理的确定性。质量的结果,通过对该数据和其他相关的,该测试系统的重要方面的数学分析的累积,可以优化算法。由此,可以尽可能有意义地表征每个测试结果。同时,在血液质量控制的应用中,“通过对压力引起的光学和随后溶血的计算和分析来量化RBC易感性”的主要技术,本发明提供了广泛的应用,例如诊断疾病是可能的。用于量化单元的质量劣化(RBC)存储的设备分别包括计算单元溶血单元和光学分析单元。类似地,溶血步骤,光学分析阶段以及用于量化本文中的单元的质量劣化(RBC)存储的相关方法包括计算步骤。 [选择图图4

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