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Antibody mimics and protein backbone for other binding proteins

机译:其他结合蛋白的抗体模拟物和蛋白骨架

摘要

PROBLEM TO BE SOLVED: To provide a new protein family being evolved to bind any compound of an object of interest.;SOLUTION: A nucleic acid encoding proteins that include an immunoglobulin fold and that can be used as scaffolds is provided. Also provided are the use method of such proteins in diagnostic methods and the use method of such protein in methods for evolving new compound-binding species and their ligands.;COPYRIGHT: (C)2009,JPO&INPIT
机译:要解决的问题:提供一个新的蛋白质家族,使其与目标对象的任何化合物结合。;解决方案:提供一种编码包含免疫球蛋白折叠且可用作支架的蛋白质的核酸。还提供了此类蛋白质在诊断方法中的使用方法以及此类蛋白质在新的化合物结合物种及其配体的进化方法中的使用方法。;版权所有:(C)2009,JPO&INPIT

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