Methods of Identifying Original and Counterfeit Articles using Micro X-Ray Diffraction Mapping

摘要

The present invention provides relatively fast, automated and non-destructive methods to screen and identify articles. The methods may be used to identify counterfeit articles, such as, for example, medications including those in the form of tablets, pills or capsules. The methods may use a micro-X ray diffraction method to scan marks as small as, for instance, 300 μm made of X-ray visible compounds. The methods may provide 2-D or 3-D maps of these marks using selected peaks from the collected X-ray diffraction patterns and may be used to certify the authenticity of drug tablets, for instance by mapping hidden marks printed under tablet coatings and on packages.