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Therapeutic pro-apoptotic BH3-like molecules and methods for generating and/or selecting the same
Therapeutic pro-apoptotic BH3-like molecules and methods for generating and/or selecting the same
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机译:治疗性促凋亡BH3样分子及其产生和/或选择方法
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摘要
The present invention relates generally to therapeutic molecules which are useful for modulating apoptosis in a target cell or cell population. More particularly, the present invention provides therapeutic agents which inhibit pro-survival molecules and which are capable of inducing or facilitating apoptosis of a target cell or cell population such as cancer cells. The present invention further provides methods for generating or selecting the therapeutic molecules and pharmaceutical compositions comprising the therapeutic molecules.
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