Monoclonal Antibodies specific for the antigen - 1 m2 of the Respiratory syncytial virus (RSV), produced and secreted by hybridoma Cell, useful for Detection and diagnosis of the infection caused by RSV

摘要

This refers to the use of specific Monoclonal Antibodies to Respiratory syncytial virus (RSV). Specifically, an IgG2a monoclonal antibody secreted by the hybridoma cell line 8a4 / G9 specifically directed to the viral Antigen m2 - 1, which is associated to the capsid of the virus.Antibodies can be used for Testing the Detection and / or determination of RSV infection. These Antibodies are found in Pure and contaminant free of any other Biological material.In Another aspect, a method is provided for the Prevention and Treatment of the infection caused by Respiratory syncytial virus (RSV) in a host, which comprises administering a composition comprising the Monoclonal Antibodies secreted by the hybridoma 8a4 / G9 in OJ SIS sufficient to prevent disease.The Humanized Antibody can be to minimize the possibility of an immune response against him in the patient who uses it. In addition, providing the formulation of any Pharmaceutical Form of the Monoclonal Antibodies secreted by the hybridoma 8a4 / G9, which are suitable for the Treatment or prevention of a disease caused by RSV.It also provides methods for diagnosis and detection of viral antigens of RSV in biological samples, in which the use of Monoclonal Antibodies by hybridoma cells produced and secreted 8a4 / G9.