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5,6-SUBSTITUTED HIV INHIBITORY PYRIMIDINS

机译:5,6-取代的HIV抑制剂嘧啶

摘要

HIV replication inhibitors of formula having HIV (Human Immunodeficiency Virus) replication inhibiting properties, the preparation thereof and pharmaceutical compositions comprising these compounds. In particular the compounds have an improved ability to inhibit the replication of mutant strains, in particular of strains that have become resistant to one or more known NNRTI drugs, which strains are referred to as drug- or multidrug-resistant HIV strains
机译:配方的HIV复制抑制剂具有HIV(人类免疫缺陷病毒)复制抑制特性的,其制备以及包含这些化合物的药物组合物。特别地,所述化合物具有提高的能力,以抑制突变菌株的复制,特别是对一种或多种已知的NNRTI药物具有抗性的菌株的复制,该菌株被称为对药物或多药具有抗性的HIV菌株。

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