Carboxylate compounds of noble metal catalytic high efficiency of IR, Ru, Rh, PD, Pt and Au

摘要

The state of expression of MSH3 to determine the responsiveness of cells to treatment quimioteru00c1pico canceru00cdgenas inhibitors of PARP and lipid of platinum. Methods are disclosed for treating a patient at risk or diagnosed with colon rectal cancer.The method of the present invention determines the general expression of MSH3 cells suspected to be cells of colon rectal cancer patient and the efficacy of therapy with a genotoxic agent antineplu00e1sico for treatment of the patient, in which a decrease in overall expression of MS. H3 in the cells of the patient when compared with expression in cells MSH3 colon - retais normal.Indicates a predisposition to responsiveness to therapy genotoxic with anticancer agent, in which the therapy includes the administration of an effective amount of a genotoxic therapy with antineoplastic agent to patients.