USE OF PC-CELL DERIVED GROWTH FACTOR (PCDGF) FOR INCREASING THE PROLIFERATION OF B CELLS

摘要

Disclosed herein are methods of increasing the proliferation of non-tumorigenic B cells. The methods involve administering PCDGF and optionallyother B cells stimulators (e.g., IgM, LPS) to B cells resulting in an increasein B cell proliferation. The methods of the invention can be used, forexample, to establish B cells lines, to sort B cells from a mixed populationof cells, or to activate resting B cells.