LIVE BRUCELLOSIS VACCINES COMPRISING ATTENUATED BRUCELLA MUTANTS

摘要

The present invention provides Brucella vaccines that protect against Brucella infections and brucellosis. These vaccines can provide cross-resistance to protect against infections by other Brucella strains. Also provided are the Brucella strains that can be used in the vaccines. Methods of inducing immunity to a Brucella infection in a mammal and of differentiating immunized mammals from unimmunized mammals are also provided.