The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using assays that detect Growth-regulated alpha protein as well as optionally one or more of Epidermal growth factor, Complement C3, Interleukin-4, Interleukin-1 alpha, Tubulointerstitial nephritis antigen, Transforming growth factor bet-1, Bone morphogenetic protein 7, Osteopontin, and Netrin-1, as diagnostic and prognostic biomarkers in renal injuries.
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