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BIOMARKERS FOR THE IDENTIFICATION OF LIVER DAMAGE

机译:识别肝损伤的生物标记

摘要

Methods and kits for characterizing liver damage in an individual are provided. The methods employ the use of immune analytes as biomarkers for detecting liver damage and predicting the likelihood that an individual suffering from liver damage will experience life-threatening liver failure. Concentration values for serum albumin and other identified immune analytes are obtained or determined from a blood sample taken from the individual. The obtained concentration values are then compared to corresponding concentrations from individuals having a healthy liver. By comparing the concentrations, an individual's likelihood of developing life-threatening liver failure and needing a liver transplant within a given time period (e.g., 6 months) can be identified.
机译:提供了表征个体肝损伤的方法和试剂盒。该方法利用免疫分析物作为生物标记物,以检测肝损害并预测遭受肝损害的个体遭受危及生命的肝衰竭的可能性。血清白蛋白和其他鉴定出的免疫分析物的浓度值是从个体血液样本中获得或确定的。然后将获得的浓度值与来自具有健康肝脏的个体的相应浓度进行比较。通过比较浓度,可以确定个体在给定时间段(例如6个月)内发生威胁生命的肝衰竭并需要进行肝移植的可能性。

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