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THERAPEUTIC AGENT AND DIAGNOSTIC AGENT FOR MITOCHONDRIAL DYSFUNCTION BRAIN DISEASES
THERAPEUTIC AGENT AND DIAGNOSTIC AGENT FOR MITOCHONDRIAL DYSFUNCTION BRAIN DISEASES
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机译:线粒体功能障碍性脑疾病的治疗剂和诊断剂
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摘要
To provide a therapeutic agent and a diagnostic agent for mitochondrial dysfunction brain diseases including cerebral infarction as a representative. A therapeutic agent for a mitochondrial dysfunction brain disease, which comprises (A) ´-aminolevulinic acid represented by the formula (1), a derivative thereof, or a salt thereof and (B) an iron compound in combination. €ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒR 2 R 1 NCH 2 COCH 2 CH 2 COR 3 €ƒ€ƒ€ƒ€ƒ€ƒ(1) wherein R 1 and R 2 each independently represents a hydrogen atom, an alkyl group, an acyl group, an alkoxycarbonyl group, an aryl group, or an aralkyl group; and R 3 represents a hydroxy group, an alkoxy group, an acyloxy group, an alkoxycarbonyloxy group, an aryloxy group, an aralkyloxy group, or an amino group.
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机译:提供以线粒体功能障碍性脑疾病为代表的线粒体功能障碍性脑疾病的治疗剂和诊断剂。线粒体功能障碍性脑疾病的治疗剂,其包含(A)由式(1)表示的β-氨基乙酰丙酸,其衍生物或其盐和(B)铁化合物的组合。€2 R 1 NCH 2 COCH 2 CH 2 COR 3€(1)其中R 1和R 2各自独立地表示氢原子,烷基,酰基,烷氧基羰基,芳基或芳烷基; R 3表示羟基,烷氧基,酰氧基,烷氧基羰氧基,芳氧基,芳烷氧基或氨基。
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