Pharmaceutical Composition for Preventing or Treating Aging-related Diseases Comprising Blocker of Progerin and Lamin A Binding and Screening Method Thereof

摘要

The present invention is novel compounds and Businesses Guerin , an active ingredient the novel compounds that inhibit the binding between the lamin A a pharmaceutical composition for preventing or treating age-related diseases , including , and relates to a screening method of binding the inhibitor to inhibit the binding between pro Guerin and lamin a, the pharmaceutical composition is a disease which is caused by the pro Guerin , in particular renal cancer , leukemia , prostate cancer , DNA repair-deficiency disorder is effective in the treatment or prevention of diseases which are caused by aging , such as an object , and kidney cancer can be screened by the screening method for a drug to inhibit the binding between pro Guerin and lamin a specifically through , leukemia , prostate cancer, can cure the disease, which is caused by the aging objects such as DNA repair-deficiency disorder develop effectively . ;