首页>
外国专利>
Alpha-sustituted omega-3 lipids that are activators or modulators of the peroxisome proliferators-activated receptor(PPAR)
Alpha-sustituted omega-3 lipids that are activators or modulators of the peroxisome proliferators-activated receptor(PPAR)
展开▼
机译:Alpha维持的omega-3脂质,是过氧化物酶体增殖物激活受体(PPAR)的激活剂或调节剂
展开▼
页面导航
摘要
著录项
相似文献
摘要
Omega-3 lipid compounds of the general formula (I): wherein R1 and R2 are the same or different and may be selected from a group of substituents consisting of hydrogen, a hydroxy group, an alkyl group, a halogen atom, an alkoxy group, an acyloxy group, an acyl group, an alkenyl group, an alkynyl group, an aryl group, an alkylthio group, an alkoxycarbonyl group, a carboxy group, an alkylsulfinyl group, an alkylsulfonyl group, an amino group, and an alkylamino group; X represents a carboxylic acid or a derivative thereof, a carboxylate, a carboxylic anhydride or a carboxamide; and Y is a C6 to C22 alkene with two or more double bonds, having E and/or Z configuration, are disclosed. Also disclosed are pharmaceutical compositions and lipid compositions comprising such compounds, and to such compounds for use as medicaments in particular for the treatment of cardiovascular and metabolic diseases.
展开▼